Creative industries topic is closely related to the art markets in a variety of mediation forms. Traditional business entrepreneurship is risk-related activities implementing innovations in markets, and generating economic growth. The creative industry area has plenty of innovation, but its acceptance is more complex because of the cultural world’s participants’ agreements. Cultural world has its own social organization, associated with the mediation (including entrepreneurship) types. The article examines the concept of entrepreneurship in the traditional business and creative industries and types of innovation and mediation (including entrepreneurship). The conclusion is that types of intermediary in creative industries depend on the cultural world’s social organization, and forms of mediation are more heterogeneous than in the traditional business.